Table 2.
Genetoype | Triggers | Genotype directed therapy |
---|---|---|
LQT1 | - exercise | -avoid competitive and exertional sports |
- tachycardia from other causes | -high efficacy of beta blockers therapy | |
LQT2 | - exercise | -remove clocks, telephones etc. from bed room |
- auditory stimuli | ||
-avoid sudden loud noises such as fire drills in school | ||
-avoid competitive and exertional sports | ||
-moderate efficacy of beta blocker therapy | ||
LQT3 | - bradycardia | -strict restriction from sports may not be necessary |
- rest/sleep | ||
-beta blockers may not be efficacious | ||
-consider adding flecainide or mexiletine | ||
-consider ICD |