Table 3.
Females
|
Males
|
|||
---|---|---|---|---|
aHRa (95% CI) | P value | aHRa (95% CI) | P value | |
TZD use | 1.57 (1.16–2.14) | 0.004 | 1.05 (0.70–1.58) | 0.817 |
Oral steroid use | 1.18 (0.92–1.53) | 0.196 | 1.32 (0.92–1.91) | 0.136 |
African-American race | 0.47 (0.35–0.62) | <0.001 | 0.55 (0.38–0.79) | 0.002 |
Married | 0.96 (0.76–1.23) | 0.756 | 1.02 (0.71–1.47) | 0.894 |
Charlson score | 1.05 (0.97–1.14) | 0.225 | 1.05 (0.96–1.16) | 0.306 |
Age | 1.06 (1.04–1.07) | <0.001 | 1.03 (1.01–1.04) | <0.001 |
Median household income | 1.00 (0.94–1.07) | 0.930 | 0.98 (0.91–1.06) | 0.666 |
Baseline CHD | 0.92 (0.60–1.41) | 0.696 | 1.13 (0.71–1.82) | 0.609 |
Baseline CHF | 1.53 (1.09–2.17) | 0.015 | 1.18 (0.73–1.89) | 0.497 |
Baseline PVOD | 1.01 (0.65–1.57) | 0.973 | 1.31 (0.81–2.17) | 0.259 |
Baseline ESRD | 3.68 (1.05–12.96) | 0.043 | 5.31 (1.95–14.49) | 0.001 |
Baseline CVAs | 1.73 (1.26–2.38) | 0.001 | 1.71 (1.15–2.78) | 0.011 |
Baseline CKD | 0.81 (0.42–1.59) | 0.548 | 1.03 (0.49–2.18) | 0.931 |
Baseline insulin useb | 1.77 (1.31–2.37) | <0.001 | 1.71 (1.15–2.56) | 0.009 |
Baseline lipid-lowering medication useb | 0.95 (0.74–1.21) | 0.675 | 0.84 (0.61–1.17) | 0.309 |
Baseline HbA1cc | 1.01 (0.94–1.07) | 0.885 | 1.08 (1.01–1.16) | 0.020 |
Multivariable models adjusted for all covariates shown in the table.
Defined as any prescription fill for these medications in the year prior to the index date.
HbA1c measurement closest to index date.