Table 3.
Quality of life
| Placebo
|
Growth Hormone
|
P value comparing change at 6-months between groups P value | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Baseline | Scoring ≤25% of normal (%) | 6 months | Scoring ≤25% of normal (%) | Baseline | Scoring ≤25% of normal (%) | 6 months | Scoring ≤5% of normal (%) | ||
| Tests in which higher scores reflect poorer quality of life | |||||||||
| QOL-AGHDA | 9.8 ± 6.2 | 9.3 ± 7.7 | 9.2 ± 6.2 | 4.0 ± 3.9 | 0.05 | ||||
| Symptom Questionnaire | |||||||||
| Anxiety | 8.2 ± 7.2 | 7.2 ± 8.4 | 5.2 ± 4.5 | 2.5 ± 3.4 | NS | ||||
| Depression | 6.8 ± 6.2 | 7.2 ± 7.8 | 4.1 ± 5.4 | 1.2 ± 1.5 | NS | ||||
| Anger/hostility | 3.6 ± 5.1 | 3.8 ± 4.5 | 2.8 ± 5.1 | 1.6 ± 2.0 | NS | ||||
| Somatic | 8.6 ± 6.0 | 10.0 ± 6.2 | 7.1 ± 4.3 | 4.2 ± 2.6 | 0.008 | ||||
| Tests in which higher scores reflect better quality of life | |||||||||
| SF-36 | |||||||||
| Physical functioning | 66.1 ± 23.4 | 47 | 63.9 ± 30.8 | 57 | 76.9 ± 17.4 | 43 | 85.4 ± 18.6 | 14 | NS |
| Role limitations due to physical health | 73.2 ± 39.8 | 33 | 62.5 ± 41.3 | 43 | 59.6 ± 40.2 | 36 | 98.1 ± 6.9 | 0 | 0.0008 |
| Bodily pain | 59.6 ± 34.4 | 53 | 61.1 ± 27.9 | 50 | 71.9 ± 22.1 | 43 | 78.1 ± 11.9 | 14 | NS |
| General health | 48.2 ± 22.8 | 47 | 48.6 ± 20.7 | 64 | 63.8 ± 18.6 | 43 | 76.8 ± 11.7 | 14 | 0.05 |
| Vitality | 39.3 ± 20.9 | 60 | 46.1 ± 26.4 | 50 | 35.8 ± 23.2 | 71 | 61.5 ± 18.9 | 21 | 0.01 |
| Social functioning | 71.4 ± 23.7 | 67 | 67.0 ± 28.0 | 64 | 74.0 ± 23.6 | 57 | 96.2 ± 7.9 | 7 | 0.008 |
| Role limitations due to emotional health | 59.5 ± 41.7 | 53 | 57.1 ± 44.2 | 57 | 82.1 ± 32.2 | 29 | 92.3 ± 14.6 | 21 | NS |
| Mental health | 64.3 ± 22.8 | 60 | 66.3 ± 24.4 | 43 | 69.8 ± 18.7 | 29 | 85.2 ± 11.2 | 7 | 0.03 |
Values are reported as mean ± sd. NS, Not significant.