Figure 2.

The relationship between recombination rate and nucleotide diversity in data from D. melanogaster and humans. The data points shown represent average nucleotide diversity for recombination rate bins. The D. melanogaster data (Shapiro et al. 2007) are from 349 loci with ≥50 synonymous sites sequenced in up to 15 African lines (as analyzed by Sella et al. 2009). The human data are from the whole-genome shotgun sequence data analyzed by Hellmann et al. (2008), analyzed in 100-kb windows and processed as described in that study. Human nucleotide diversity is corrected for differences in interspecific divergence (to account for differences in mutation rate) (Hellmann et al. 2003). Drosophila diversity is not corrected for divergence—the correlation between recombination and divergence was weakly negative for this data set (Sella et al. 2009). For both data sets, recombination rate bins were defined manually based on data availability and log-scale bin width.