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. Author manuscript; available in PMC: 2010 Mar 17.
Published in final edited form as: Exp Gerontol. 2009 Sep 29;45(1):15–22. doi: 10.1016/j.exger.2009.09.007

Scheme 1.

Scheme 1

Selective alteration of functional synaptic proteins, e.g., a-type synapsin in synapses that are morphologically present may be an underlying mechanism in MCI cognitive impairment.