Figure 4.

Specificity of CD spectral shifts with different PrP peptides. Predicted (−−), actual (—), and individual spectra as in Fig. 1. Reactions were performed as in Fig. 2, except that the buffer used was 20 mM Tris, 10 mM MgSO₄, 50 mM KCl, and 1.25 mM ATP at pH 7.5 to approximate ATPase assay conditions.