Table 2.

Table 2(a). Ultrasound criteria for diagnosis of ADPKD^*

Age	PKD1	PKD2	Unknown ADPKD Gene Type
15-30	≥3 cysts**
	PPV=100%	PPV=100%	PPV=100%
	SEN=94.3%	SEN=69.5%	SEN=81.7%
30-39	≥3 cysts**
	PPV=100%	PPV=100%	PPV=100%
	SEN=96.6%	SEN=94.9%	SEN=95.5%
40-59	≥2 cysts in each kidney
	PPV=100%	PPV=100%	PPV=100%
	SEN=92.6%	SEN=88.8%	SEN=90%
Table 2(b). Ultrasound criteria for exclusion of ADPKD*
Age	PKD1	PKD2	Unknown ADPKD Gene Type
15-30	≥1 cyst
	NPV=99.1%	NPV=83.5%	NPV=90.8%
	SPEC=97.6%	SPEC=96.6%	SPEC=97.1%
30-39	≥1 cyst
	NPV=100%	NPV=96.8%	NPV=98.3%
	SPEC=96%	SPEC=93.8%	SPEC=94.8%
40-59	≥1 cyst
	NPV=100%	NPV=100%	NPV=100%
	SPEC=93.9%	SPEC=93.7%	SPEC=93.9%

^*Derived from J Am Soc Nephrol 20: 205-212;

^**Unilateral or bilateral.

PPV (positive predictive value); SEN (sensitivity); NPV (negative predictive value); SPEC (specificity) – all values presented are mean estimates. For 95% confident intervals, please refer to the above paper.