Table II. Semi-quantitative analysis of S100A7 Immunostaining.
Mean semiquantitative scores of S100A7 staining in epithelium, glands, and subepithelial stroma
The difference between the groups is displayed in the Kruskal-Wallis ANOVA on ranks. The p values in italics reflect post hoc comparison with normal samples, with statistically significant values in bold. S100A7 staining was significantly decreased in epithelium, glands, and subepithelial stroma in CRSwNP, CRSsNP, and polyp tissue compared with normal samples. Among the groups, polyp tissue showed the least staining in all areas.
CRSwNP (n = 11) | CRSsNP (n = 10) | Polyp (n = 10) | Normal (n = 7) | Kruskal-Wallis ANOVA p Value | |
---|---|---|---|---|---|
Epithelium (scale = 0–3) |
1.55 p < 0.01 |
1.8 p < 0.01 |
0.7 p < 0.001 |
2.57 | < 0.0001 |
Glands (scale = 0–3) |
1.60 p < 0.01 |
2.15 p = 0.0539 |
1.39 p < 0.01 |
2.86 | < 0.01 |
Subepithelial stroma (scale = 0–3) |
1.10 p < 0.01 |
1.45 p < 0.05 |
0.85 p < 0.01 |
2 | < 0.001 |
Total (scale = 0–9) |
4.25 p < 0.01 |
5.4 p < 0.01 |
2.94 p < 0.01 |
7.43 | < 0.0001 |