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. Author manuscript; available in PMC: 2011 Mar 16.
Published in final edited form as: Dev Cell. 2010 Mar 16;18(3):450–462. doi: 10.1016/j.devcel.2009.12.023

Figure 1.

Figure 1

BCL6 interacts with the ANK domain of Notch1.

A: Lane 1: GST/embryonic protein extract, Lane 2: GST-ANK, and Lane 3: GST-ANK/embryonic protein extract. a: BCL6 and c: β-actin. GST-ANK is indicated by an asterisk. B: Protein extracts from stage 25 embryos were incubated with α-Notch1 or α-BCL6 antibody. Mouse IgG was used for a mock immunoprecipitation. C: GST-BCL6 constructs. The numbers on the top indicate the positions of amino acids. D: The top panel shows the expression of GST constructs and the bottom panel shows the interactions between Flag-tagged NICD (Flag-NICD) and GST-BCL6 constructs. Each arrowhead indicates an intact GST fusion protein.