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. Author manuscript; available in PMC: 2011 Mar 12.
Published in final edited form as: Mol Cell. 2010 Mar 12;37(5):643–655. doi: 10.1016/j.molcel.2010.02.007

Figure 4. Tie1 and Tie2 form a direct interaction as demonstrated by allelic suppression.

Figure 4

HEK293 cells were transfected with the following mutant receptor pairs A) Tie1-YFP B1 and Tie2-CFP C2 or B) Tie1-YFP C1 and Tie2-CFP A2, and monitored by confocal microscopy. C) The average FRET efficiencies from experiments in A–B. Data are represented as mean +/− SEM. * Images are as described in Figure 1.