Table 1.
Distribution of CVD risk factor status in stroke patients and their controls
| Stroke patients (n = 183) | Non-stroke patients (n = 164) | |||
|---|---|---|---|---|
| Variables | N (%) | N (%) | P | |
| Gender | Male | 114 (62.3) | 87 (53.1) | 0.0815 |
| Diabetes | Yes§ | 64 (35.0) | 19 (11.6) | <0.0001*** |
| Hypertension | Yes& | 151 (82.5) | 90 (54.9) | <0.0001*** |
| TC | ≧240 mg/dL+ | 26 (14.2) | 32 (19.5) | 0.1861 |
| Triglyceride | ≧200 mg/dL+ | 44 (24.0) | 38 (23.2) | 0.8480 |
| LDL-C | ≧130 mg/dL+ | 52 (28.4) | 66 (40.2) | 0.0202* |
| HDL-C | <40/50 mg/dL in male/female | 131 (71.6) | 68 (41.5) | 0.0001*** |
| TC/HDL-C ratio | ≧5+ | 66 (36.1) | 58 (35.4) | 0.8920 |
| Smoker | Ever (current/past) | 73 (39.9) | 47 (28.7) | 0.0804 |
| BMI | ≧27 | 23 (12.6) | 40 (24.4) | 0.0043** |
| Plaque score | ≧3 | 83 (45.3) | 43 (26.2) | 0.0002*** |
| Genotype | L: >26 GT repeats | 138 (75.4) | 114 (69.5) | 0.4262 |
§ fasting blood glucose ≧126 mg/dL or on DM medication. &SBP ≧140 mmHg or DBP ≧90 mmHg or on anti-hypertension medication. + included those patients with related medication. TC: total cholesterol; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; BMI: body mass index. P: the p value from chi-square test between stroke and non-stroke patients. Genotype; the length of GT repeats in HO-1 gene promoter. *: p < 0.05; **: p < 0.01; ***: p < 0.001