Table 1.
Clinico-pathological characteristics of the laryngeal squamous cell carcinomas and correlations with podoplanin expression.
| Parameter | No (%) | Low podoplanin expression (%) | High podoplanin expression (%) | P |
|---|---|---|---|---|
| Tumour site | ||||
| - Supraglottis | 23 (43) | 19 (83) | 4 (17) | 0.01 |
| - Glottis | 30 (57) | 14 (47) | 16 (53) | |
| pT classification | ||||
| - T1 | 14 (26) | 5 (36) | 9 (64) | 0.033 |
| - T2 | 13 (25) | 7 (54) | 6 (46) | |
| - T3 | 17 (32) | 13 (76) | 4 (24) | |
| - T4 | 9 (17) | 8 (89) | 1 (11) | |
| pN classification | ||||
| - N0 | 38 (72) | 23 (61) | 15 (39) | 0.53 |
| - N1-3 | 15 (28) | 10 (67) | 5 (33) | |
| Disease stage | ||||
| - I | 16 (30) | 5 (31) | 11 (69) | 0.006 |
| - II | 9 (17) | 5 (56) | 4 (44) | |
| - III | 10 (19) | 7 (70) | 3 (30) | |
| - IV | 18 (34) | 16 (89) | 2 (11) | |
| Degree of differentiation | ||||
| - Well differentiated | 32 (60) | 16 (50) | 16 (50) | 0.04 |
| - Moderately differentiated | 16 (30) | 13 (81) | 3 (19) | |
| - Poorly differentiated | 5 (10) | 4 (80) | 1 (20) | |
| Recurrence | ||||
| - No recurrence | 42 (79) | 25 (60) | 17 (40) | 0.42 |
| - Loco-regional recurrence | 7 (13) | 4 (57) | 3 (43) | |
| - Distant metastasis | 4 (8) | 4 (100) | 0 (0) |