Table 1.

Correlation between CD68TF_Hotspot and clinicopathologic characteristics.

Variable	CD68TFHotspot				P value
	-/+	+	++	+++
	1	2	3	4
Gender
Male	23	21	37	13	0.939
Female	15	13	27	11
Age (years)
< 60	22	17	26	15	0.195
≥ 60	16	17	38	9
Sites of primary tumors
Left	25	14	40	16	0.107
Right	13	20	24	8
TNM stages
IIIB	17	18	46	17	0.025*
IV	21	16	18	7
Invasive depth
T3	31	30	53	17	0.422a
T4	7	4	11	7
Hepatic metastasis(1)
No	13	14	42	16	0.004*
Yes	25	20	22	8
Hepatic metastasis(2)
No	13	14	42	16	0.001*b
Metachronous	4	4	4	1
Synchronous	21	16	18	7
Grade
G1	1	1	1	0	0.124b
G2	23	21	48	21
G3	14	11	14	2
G4	0	1	1	1
Pathologic classification
Papillary + tubular	28	25	57	23	0.022*a
Mucoid + signet ring	10	9	7	1
Growth pattern
Pushing	19	8	18	8	0.071
Infiltrating	19	26	46	16

*: p < 0.05. a: Likelihood ratio. b: Exact linear-by-linear association test.