Table 3.
GSK3B IVS2−68G>A Allele Frequencies in Cases and Control Subjectsa
| Participants | G Allele | A Allele |
|---|---|---|
| Healthy | 163 (156) | 7 (6) |
| Affected, with AD and FTD | 264 (242) | 36 (30) |
| All affected, with AD, FTD, and PPA | 332 (306) | 44 (36) |
Abbreviations: AD, Alzheimer disease; FTD, frontotemporal dementia: PPA, primary progressive aphasia.
a
Alleles for AD, FTD, and PPA were combined as described In the text. Values are expressed as allele frequencies in total samples (allele frequencies in white samples only). Affected groups (both excluding and Including PPA) were significantly different from the healthy control subjects at the P < .005 level using a 2-tailed Fisher exact test.