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. 2010 Feb 23;10:61. doi: 10.1186/1471-2407-10-61

Table 2.

Types of canine mammary columnar cell lesions and associated neoplastic alterations.

Tumor types(**) CCC(%) CCH(%) FEA(%) Total(%)
invasive carcinomas 12 (30.7) - 5 (19.2) 19 (28.4)
carcinoma in benign tumor 6 (15.3) 2 (100) 3 (11.5)
solid carcinoma 2 (5.1) - 2 (7.2)
tubulopapillary carcinoma 4 (10.3) - -
ductal carcinoma in situ 7 (17.9) - 13 (50.0)(*) 20 (29.8)
benign tumors 18 (46.1)(*) 3 (11.5) 21 (31.4)
simple adenoma 3 (7.6) - -
duct papilloma 7 (17.9) - 1 (3.8)
benign mixed tumor 8 (20.6) - 2 (7.7)
without tumor 2 (5.1) - 5 (19.2) 7 (10.4)
Total 39 (100) 2 (100) 26 (100) 67 (100)

(*)Flat epithelial atypia presence is often associated with in situ carcinomas and columnar cell lesion without atypia are more frequent in benign tumors (P < 0,05).

(**)Misdorp,1999. International Histological Classification of Tumors of Domestic Animals.

CCC: columnar cell change without atypia; CCH: columnar cell hyperplasia without atypia; FEA: flat epithelial atypia