Table 1.

The EC₅₀ Values for the effects of trichostatin A on apoptosis in eosinophils and neutrophils.

	EC50 (nM)
Apoptosis	Eosinophils	neutrophils	P value
GM-CSF
0.01 ng/ml	79 ± 2
0.1 ng/ml	102 ± 1
10 ng/ml	93 ± 1	123 ± 9	0.0042
IL-5	92 ± 8
Constitutive	34 ± 10	97 ± 22	0.0007
Budesonide	32 ± 17	99 ± 7	0.026
Fluticasone	47 ± 15	100 ± 11	0.017
Mometasone	20 ± 5	87 ± 9	< 0.0001
Fas	31 ± 10

Values are the mean ± S.E.M. of six duplicate experiments with cells isolated from different donors.