Comparison of the Ki values of the purified PPPK-DHPS enzymes for sulfadoxine with sulfathiazole, sulfamethoxazole, and dapsone. The correlation coefficients are sulfadoxine:sulfathiazole, 0.99; sulfadoxine:sulfamethoxazole, 1.0; and sulfadoxine:dapsone, 0.96; and the slopes for each plot are 0.99, 0.87, and 0.89, respectively.