Table 1.
Genotypes and sulfadoxine sensitivity of P. falciparum lines and genotypes of DHPS constructs
| Isolate | Origin | Sulfadoxine | Amino acid
|
Construct | Reference | ||||
|---|---|---|---|---|---|---|---|---|---|
| 436 | 437 | 540 | 581 | 613 | |||||
| D10, HB3, ItG2, M24, NF7 | PNG, Africa, Brazil | S | S | A | K | A | A | D10-C | (7, 8) |
| 3D7 | Africa | R | S | G | K | A | A | 3D7-C | (7, 22) |
| Tak9/96 | SE Asia | R | A | G | K | A | A | Tak9/96-C | (22) |
| K1 | SE Asia | R | S | G | K | G | A | K1-C | (7) |
| W2mef, Dd2 | SE Asia | R | F | G | K | A | S | W2mef-C | (7) |
| PR145, 336, 338, 342, 345, 347 | Thailand | ND | A | G | E | A | A | PR145-C | This publication |
| PR327, 343, 352 | Thailand | ND | S | G | E | G | A | This publication | |
| PR346 | Thailand | ND | A | G | E | G | A | This publication | |
| S | A | K | G | A | D10-C/G581 | ||||
| S | G | E | A | A | 3D7-C/E540 | ||||
ND, not determined.