Table 2.
Regions in which theta power differed between youth with bipolar disorder and healthy controls following presentation of negative and positive feedback
| Region | BA | X,Y,Z | Between-group comparison of neural activation | t value | p value |
|---|---|---|---|---|---|
| Anterior Cingulate Cortex (ACC): L | 10/9 | 1,47,14 | Pos. fdbk.: CON > BD | -3.42 | .0009 |
| Anterior Cingulate Cortex (ACC): R | 32 | 17,31,28 | Neg. fdbk.: BD > CON | 2.99 | .004 |
| Inferior Parietal Lobule (IPL): L | 40 | -55,-43,35 | Neg. fdbk.: BD > CON | 2.83 | .006 |
| Superior Parietal Lobule (SPL): R | 7 | 20,-67,45 | Neg. fdbk.: BD > CON | 3.16 | .002 |
Note. Regions identified based on significant group (BD vs. CON) × feedback type (negative vs. positive) ANOVA interaction. Greater theta band power = greater neural activation; BA=Brodmann Area; X,Y,Z = Talairach space coordinates reflecting the peak voxel of that region; L = left; R = right; Pos. fdbk. = after positive feedback; Neg. fdbk. = after negative feedback; BD = bipolar disorder; CON = control.