Table 7.

Comparative characteristics of FFA and ICG features of white dot syndrome[52]

	APMPPE	Birdshot	PIC	MEWDS	MFC	GHPC	POHS
FFA active	Early hypofluorescence and late hyperfluorescence	Mild hyperfluorescence and staining in late phase	Early hypofluorescence and late hyperfluorescence	Early patchy punctate hyperfluorescence with late deep staining of RPE and peripapillary area. Leakage from optic disk and retinal capillaries. Early fluorescence-wreathlike pattern. Choroidal background fluorescence between lesions is normal	Early hypofluorescence and late hyperfluorescence	Early hypofluorescence and late hyperfluorescence. Choroidal vessels are easily seen	Early hypofluorescence and late hyperfluorescence. Confirms CNVM
FFA inactive	Window defects	Window defects	Window defects	Window defects	Window defects. Early hyperfluorescence and late staining	Window defects	Window defects
ICG-active	Marked choroidal hyperfluorescence in both early and late phase. Large choroidal vessels seen	-	CNVM reveals hyperfluorescence	Multiple hypofluorescent spots in the posterior pole and hyperfluorescence around optic nerve head, especially in patients with enlarged blind spots	Hypofluorescent CNVM reveals hyperfluorescence	-	-
ICG-active	Choroidal hypofluorescence	-	-	Hypofluorescent spots persist until patient recovers	Hypofluorescent.	-	-
ERG/VEP	-	unilateral negative ERG	-	markedly reduced a wave and early receptor potential amplitudes suggesting primary involvement of RPE	-	-
Visual fields	-			Enlargement of blind spot No correlation of field defects with lesions