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. 2009 Dec 2;29(48):15073–15082. doi: 10.1523/JNEUROSCI.4748-09.2009

Figure 1.

Figure 1.

Expression of olig2 mRNA is increased in the lesioned adult spinal cord close to the lesion site at 2 weeks postlesion. A, Schematic presentation of transcription factor domains set up in the developing vertebrate neural tube by a ventrodorsal gradient of Shh (modified after Vallstedt and Kullander, 2007). Different progenitor zones (p0–3) give rise to distinct classes of interneurons (V0–3). The pMN zone gives rise to motor neurons (MN). B, Cross-sections through the adult spinal cord are shown at the level of the central canal (dorsal is up). Ventricular cells in ventrolateral positions around the central canal express detectable levels of olig2 mRNA in the lesioned spinal cord. Scale bar, 25 μm.