Skip to main content
. Author manuscript; available in PMC: 2011 Mar 24.
Published in final edited form as: J Am Chem Soc. 2010 Mar 24;132(11):3680–3681. doi: 10.1021/ja1010866

Table 2.

Amide-Directed Olefination of sp3 C–H Bondsa,b

graphic file with name nihms183619f3.jpg
a

Conditions: 0.2 mmol of substrate, 0.1 mL of benzyl acrylate, 10 mol % Pd(OAc)2, 2.0 equiv of LiCl, 1.1 equiv of Cu(OAc)2, 1.1 equiv of AgOAc, 1 mL of DMF, 120 °C, N2, 12 h.

b

Isolated yield,.

c

Obtained as a mixture of inseparable cis/trans diastereomers (see Supporting Information). Optically inactive starting materials were used.

d

Yield determined by 1H NMR.