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. Author manuscript; available in PMC: 2010 Sep 4.
Published in final edited form as: Nature. 2010 Mar 4;464(7285):121–125. doi: 10.1038/nature08778

Figure 2. Abnormal accumulation of acylcarnitines and triglyceride in the livers of mice lacking SIRT3 during fasting.

Figure 2

a, b. Metabolomic analyses were conducted on mouse liver tissue (a) and plasma (b), data obtained in SIRT3-/- mice are shown relative to wt mice (n=5/genotype, fasted 24 h); c. Livers extracts from SIRT3-/- and wt mice were analyzed for total phospholipids, triglycerides and cholesterol esters (n=5/genotype, fed or fasted 24 h), *p<0.05