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. Author manuscript; available in PMC: 2010 Sep 4.
Published in final edited form as: Nature. 2010 Mar 4;464(7285):121–125. doi: 10.1038/nature08778

Figure 5. Mice lacking SIRT3 show reduced ATP production, cold intolerance and hypoglycemia.

Figure 5

a. Hepatic ATP levels were measured in fed and fasted wt and SIRT3-/- mice (n=5/genotype/condition) b, c. Core temperature (b) and blood glucose (c) were measured in fed and fasted wt and SIRT3-/- mice exposed to cold (4°C) for 6 h (n=5/genotype/condition); *p<0.05, **p<0.01