Skip to main content
. Author manuscript; available in PMC: 2011 Mar 15.
Published in final edited form as: Chem Res Toxicol. 2010 Mar 15;23(3):608–619. doi: 10.1021/tx900351q

Figure 4.

Figure 4

Representative 13C-NMR spectra of water-soluble metabolites from control and immunosuppressant-treated C6 glioma cells. The cells were incubated with 5mM [1-13C]glucose for 3 hours. Treatment with immunosuppressants occurred at the same time (500 µg/L CsA, 100 µg/L SRL or 100 µg/L RAD alone or in combination with CsA for 3 hours and addition of 1 mM H2O2 for 30 minutes). Changes in metabolites are marked by arrows. Abbreviations: Ala: alanine, Asp: aspartate, Gln: glutamine, Glc: glucose, Glu: glutamate, Lac: lactate, myo-Ins: myo-inositol (natural abundance).