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Paired pulse depression was affected by muscimol and TPMPA Testing for paired pulse depression (PPD) in 12 Pyramidal cells by using an interstimulus interval of 100 ms. TPMPA increased the PPD of EPSCs by 35.6 ± 7.3% (p < 0.05). Muscimol significantly increased the PPD ratio and of IPSCs by 42.5 ± 5.2% (p < 0.05) and increased the PPF ratio of EPSCs by 39.2 ± 3.9% (p < 0.05).
