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. 2010 Mar 9;5:117–128. doi: 10.2147/ijn.s9155

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© 2010 Lin et al, publisher and licensee Dove Medical Press Ltd.

This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.

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Confocal laser scanning microscopic (CLSM) micrographs of nude mouse skin after the in vivo topical administration of sulforhodamine B (SRB) via the skin for 2 hours from 30% ethanol (control) without fluorescein isothiocyanate (FITC) loading (A) NLC-5P without FITC loading (B) 30% ethanol (control) with FITC loading (C) NLC-5P with FITC loading (D).

Notes: The skin specimen was viewed by CLSM at ∼10-μm increments through the Z-axis from skin surface. The arrows indicate the skin fragments from surface to bottom.