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Table 2.

Blood cell counts at different ages for DR.+/+ and DR.lepr−/lepr− rats

45 Days
180 Days
DR.+/+ DR.lepr−/lepr− P value DR.+/+ DR.lepr−/lepr− P value
WBC, K/μl 5.9 ± 0.85 4.5 ± 0.51 ns 6.96 ± 0.4 6.68 ± 1.4 ns
RBC, M/μl 7.01 ± 0.12 5.97 ± 0.03 * 7.66 ± 0.3 8.32 ± 0.4 ns
HGB, g/dl 15.1 ± 0.28 13.77 ± 0.11 ns 15.04 ± 0.5 15.8 ± 0.76 ns
HCT,% 51.4 ± 0.99 47.52 ± 0.32 ns 50 ± 1.9 53.3 ± 3.19 ns
MCV, fl 73.3 ± 0.56 79.83 ± 0.31 * 65.6 ± 1 63.8 ± 1.07 ns
MCH, pg 21.5 ± 0.1 23.05 ± 0.08 * 19.68 ± 0.3 19.1 ± 0.19 ns
MCHC, % 29.3 ± 0.16 28.85 ± 0.3 ns 30.14 ± 0.4 29.9 ± 0.55 ns
Polys, % 8.43 ± 1.19 15.5 ± 3 * 7.75 ± 1.2 13.5 ± 0.29 *
Lymph, % 88.9 ± 1.79 81.17 ± 2.48 * 89 ± 1.5 82 ± 1.22 *
Monos, % 2.43 ± 0.68 3.33 ± 0.67 ns 3 ± 0.4 3.5 ± 1.19 ns

Data represent means ± SE for n = 6 rats/group at 45 days of age and 5 rats/group at 180 days of age. Data are combined for male and female rats. WBC, white blood cells; RBC, red blood cells; HGB, hemoglobin; HCT, hematocrit; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; Polys, polymorphonuclear cells; Lymph, lymphocytes; Monos, monocytes. P values were determined by Student's t-test.

*

P < 0.05.