Fig. 4.

Effect plot for marker D1Rat112 on phenotype Glucose_AUC in HS rats. SSLP genotypes are shown on the x-axis (note that 4 alleles were found in the HS for this marker). Glucose_AUC is shown on the y-axis, with means ± SE for animals within each genotype group plotted on the graph. Founder allele sizes are listed in the graph. Note that the 133 allele (ACI and WN) appears to protect against high glucose, while HS animals with either the 161 (WKY) the 172 (F344) allele exhibit significantly higher glucose levels during the glucose tolerance test than those with the other alleles, except when heterozygous with the protective 133 allele. The BN allele at this locus, 157, was not represented within the HS colony.