Table I.
Library | Design |
Diversity |
||||
---|---|---|---|---|---|---|
BC | DE | FG | BC | DE | FG | |
WT | DAPAVTVRY | GSKST | GRGDSPASSK | 1 | 1 | 1 |
NNB | X6–9Y | X4–7 | X5,6,8,10 | 5 × 1011 | 1 × 109 | 1 × 1013 |
YS | (S|Y)7–10 | gsX0,1,3st | (S|Y)6,7,8,10 | 2 × 103 | 1 × 109 | 1 × 103 |
WT, wild-type sequence; X, any amino acid; S|Y, either serine or tyrosine; g, 50% glycine, 50% any other amino acid (analogous for s, t); subscripts refer to the number of amino acids.