Table 5.
Multivariate analysis by Cox proportional hazard regression model for the evaluation of prognostic factors.
| Variable (No. of patients) |
No. of dead patients |
Hazard ratio | 95% confidence interval | P |
|---|---|---|---|---|
| (5-yr survival cut-off) | (HR) | (CI) | ||
| Age in years | ||||
| ≤ 57 (25) | 21 | 1 | ||
| >57 (26) | 22 | 1.25 | 0.62-2.48 | 0.533 |
| PN expression | ||||
| Low (22) | 17 | 1 | ||
| High (29) | 26 | 2.02 | 1.02-4.02 | 0.045* |
| Lymph node metastasis | ||||
| Absence (36) | 28 | 1 | ||
| Presence (15) | 15 | 3.13 | 1.54-6.35 | 0.002* |
| Histological type | ||||
| Well-differentiated (20) | 16 | 1 | ||
| Moderately-differentiated (8) | 8 | 2.77 | 1.10-6.98 | 0.031* |
| Poorly-differentiated (8) | 7 | 1.64 | 0.63-4.29 | 0.310 |
| Papillary (15) | 12 | 0.60 | 0.25-1.44 | 0.254 |
| Tumor size (cm) | ||||
| ≤ 5 (28) | 23 | 1 | ||
| >5 (23) | 20 | 1.49 | 0.76-2.94 | 0.251 |
* P value of equal or less than 0.05 means statistical significance