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Both the GC-rich Hfx. volcanii genome and the AT-rich Hqr. walsbyi genome are “evolving away” from their respective IS elements. Plot of GC content (black) overlaid with GC content of IS elements (yellow) for the Hfx. volcanii main chromosome (A), Hfx. volcanii pHV4 (B), and Hqr. walsbyi main chromosome (C).
