Table 2.
Adjusted risks of outcomes associated with the hepatitis coinfection*
| Outcome | Ratio or coefficient | 95% confidence interval | p |
|---|---|---|---|
| Hepatotoxicity | |||
| Grade ≥2† | 2.94 | 1.49-5.81 | 0.002 |
| Grade ≥3† | 2.18 | 0.61-7.75 | 0.2 |
| Highest grade‡ | 1.83 | 1.28-2.60 | 0.001 |
| CD4 cell count increase|| | |||
| Primary slope | 0.02 | -0.20 to 0.24 | 0.9 |
| Secondary slope¶ | -0.04 | -0.38 to 0.31 | 0.8 |
| Quadratic effect¶ | 0.00 | -0.00 to 0.01 | 0.8 |
| Viral load < 400 copies/mL† | 1.00 | 0.68-1.47 | 0.9 |
| Death† | 0.52 | 0.14-1.93 | 0.3 |
| Death or new AIDS-defining event† | 0.37 | 0.11-1.29 | 0.1 |
* Coinfected patients versus monoinfected patients. † Cox regression. ‡ Poisson regression. || Mixed-effect linear regression of the square root-transformed CD4 cell count. ¶ From 6 months to 24 months, combined with the primary slope.