Table 4.
The ten most coherent TFBS-cluster gene signatures according to the Ingenuity softwarea
| p-value | |
|---|---|
| GC, ETF, AP2GAMMA, MOVB, AP2, LRF, CHCH, SP1, AP2LAPHA | |
| Cellular Development (MCF) | 4.32E-13 |
| Organ Development (PSDF) | 2.43E-14 |
| Wnt/b-catenin Signaling(CP) | 3.90E-10 |
| CKROX, SPZ1, WT1, MZF1, MAZ, TFIII, IK | |
| Cellular Development (MCF) | 3.97E-12 |
| Tissue Development (PSDF) | 1.23E-12 |
| Wnt/b-catenin Signaling (CF) | 1.51E-05 |
| AML, COREBINDINGFACTOR, PEBP, OSF2, AML1 | |
| Cell-To-Cell Signaling and Interaction (MCF) | 5.29E-05 |
| Hematological System Development and Function (PSDF) | 3.08E-05 |
| Immune Cell Trafficking (PSDF) | 3.08E-05 |
| CACBINDINGPROTEIN, CACD, PAX4, SREBP1 | |
| Cellular Development (MCF) | 6.48E-12 |
| Organismal Development (PSDF) | 4.92E-16 |
| Axonal Guidance Signaling (CP) | 4.26E-05 |
| HMGIY, STAT6, STAT1, NFAT | |
| Cellular Development (MCF) | 2.43E-08 |
| Nervous System Development and Function (PSDF) | 6.45E-18 |
| Axonal Guidance Signaling (CF) | 4.24E-04 |
| CEBPDELTA, CEBPB, CEBPA | |
| Antigen Presentation (MCF) | 4.28E-04 |
| Humoral Immune Response (PSDF) | 2.98E-04 |
| T Helper Cell Differentiation (CP) | 1.61E-03 |
| ZF5, E2F, KROX | |
| Gene Expression (MCF) | 6.32E-22 |
| Organ Development (PSDF) | 5.59E-16 |
| Axonal Guidance Signaling (CP) | 1.13E-12 |
| ZTA, BACH2, BACH1 | |
| Antigen Presentation (MCF) | 1.35E-06 |
| Cell-mediated Immune Response (PSDF) | 1.35E-06 |
| NF-kB Signaling (CP) | 1.71E-03 |
| CREL, NFKAPPAB65 | |
| Cell-To-Cell Signaling and Interaction (MCF) | 2.73E-05 |
| Cell-mediated Immune Response (PSDF) | 1.81E-06 |
| NF-kB Signaling (CP) | 4.28E-06 |
| MAZR, ZNF219 | |
| Cellular Development (MCF) | 9.61E-13 |
| Nervous System Development and Function (PSDF) | 1.23E-10 |
| Axonal Guidance Signaling (CP) | 1.40E-07 |
a Only the top categories with respect to p-value are given