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. Author manuscript; available in PMC: 2010 Sep 18.
Published in final edited form as: Oncogene. 2009 Dec 7;29(11):1588–1597. doi: 10.1038/onc.2009.452

Figure 5. Rapamycin improves survival of LSL-KrasG12D Tsc1L/L and LSL-KrasG12D Tsc1L/+ mice.

Figure 5

Kaplan-Meier survival curves of mice of two genotypes treated with either rapamycin (6 mg/kg IP every other day) or placebo, beginning 9 weeks following AdCre inhalation. Rapamycin significantly extended the survival of both LSL-KrasG12D Tsc1L/L (p=0.0018) and LSL-KrasG12D Tsc1L/+ mice (p=0.002).