Table 3.
Baseline and two months six minutes walk distance of the two studied groups of COPD patients
Outcome measure | Group 1 (Rehabilitation group) N = 25 | Group 2 (Usual care control group) N = 14 | Mean differences between groups (95% CI) | P value | ||
---|---|---|---|---|---|---|
Enroll | 2 months | Enroll | 2 months | |||
Six minutes walk distance in meters | ||||||
Mean ± SD | 88.79 ± 19.14 | 141.71 ± 23.11 | 83.79 ± 15.9 | 68.56 ± 32.11 | 58.15 ± 11.23 | < 0.001# |
Chronic respiratory disease questionnaire$ | ||||||
Dyspnea (range 5-35) | 11.8 ± 5.0 | 19.6 ± 5.2* | 12.4 ± 4.4 | 13.5 ± 4.3 | 5.5 (3.0-9.0) | 0.003^ |
Fatigue (range 4-28) | 9.8 ± 2.8 | 17.4 ± 5.4* | 11.6 ± 6.1 | 13.2 ± 5.1 | 5.3 (1.9-9.8) | 0.004^ |
Emotion (range 7-49) | 22.1 ± 5.8 | 33.5 ± 7.2* | 27.0 ± 12.6 | 29.7 ± 11.4 | 8.7 (2.5-15.0) | 0.008^ |
Short form 36 (range 0-100)$ | ||||||
Physical component | 30.6 ± 14.2 | 56.3 ± 24.0* | 40.6 ± 21.9 | 47.2 ± 24.2 | 20.1 (3.3-36.8) | 0.02§ |
Mental component | 26.3 ± 14.6 | 39.0 ± 20.0* | 30.4 ± 19.9 | 32.4 ± 22.2 | 10.6 (-0.3-21.6) | 0.047§ |
Pulmonary function tests (spirometry) | ||||||
FVC (L/min) | 1.37 ± 0.50 | 1.42 ± 0.59 | 1.09 ± 0.41 | 0.98 ± 0.20 | 0.44 (0.11-0.77) | 0.01^ |
FVC (% pred) | 36.24 ± 14.17 | 40.4 ± 16.16 | 29.0 ± 10.91 | 26.57 ± 7.13 | 13.83 (2.5-14.9) | 0.00^ |
FEV1 (L/min) | 0.80 ± 0.35 | 0.83 ± 0.52 | 0.62 ± 0.18 | 0.64 ± 0.20 | 0.19 (-0.1-0.48) | 0.2§§ |
FEV1 (%pred) | 29.44 ± 13.14 | 29.92 ± 20.21 | 23.21 ± 7.70 | 23.14 ± 7.56 | 6.78 (-5.01-18.57) | 0.25§§ |
#Data expressed as mean score (SD);
Increased score denotes improvement; P < 0.05 between baseline and two months in rehabilitation group using paired t test;
P < 0.001 between group 1 and group 2 after two months of enrolment using unpaired t tests;
P < 0.01 between group 1 and 2 after two months of enrolment using unpaired t tests;
P < 0.05 enroll vs 2 months in group two using paired t tests;
P < 0.05 between group 1 and 2 after twomonths of enrolment using unpaired t tests;
P > 0.05 between group1 and 2 after two months of enrolment using unpaired t tests, COPD = Chronic obstructive pulmonary disease