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Overall (a, c) Rosetta and (b, d) dDFIRE energy histograms for the real protein controls (black), novel decoy scaffolds (light gray), and the compact random coil controls (dark gray). (a, b) Show the energies for the “real,” “decoys,” and “random” original design protocol sets, whereas (c, d) show the energies for the “real2” and “decoys2” design protocol sets.
