Table 2.

Top 15 antigens out of 29 candidate antigens found immunogenic in pancreatic cancer compared to healthy donor sera

Locus	Symbol	Frequency in healthy,%	Frequency in pancreatic,%	Intensity* healthy	Intensity* pancreatic	Overall score†
BC032539.1	MAPK9	0	8	1.00	2.33	11.0
BC041421.1	NR2E3	4	13	1.94	1.55	10.7
NM_153344.1	C6orf141	0	8	1.00	1.96	10.4
NM_002752.3	MAPK9	0	8	1.00	1.60	9.8
NM_004560.2	ROR2	4	12	1.25	1.68	9.8
NM_080840.1	PTPRA	0	7	1.00	3.10	9.7
BC063126.1	FAM13A1	0	5	1.00	6.58	9.4
BC037982.1	LRRC49	0	7	1.00	2.78	9.4
NM_017886.1	ULK4	0	7	1.00	2.14	8.6
BC002660.1	TMOD1	2	7	1.10	3.83	8.5
NM_177553.1	GAS2	2	8	1.11	1.65	7.9
NM_052958.1	C8orf34	0	7	1.00	1.48	7.6
NM_020954.1	KIAA1618	2	8	2.77	1.64	7.2
BC028124.1	C17orf46	0	5	1.00	2.88	7.1
BC009739.1	HERPUD1	0	5	1.00	2.77	7.0

See complete list in Table S2.

*Intensity represents the average ratio of observed reactivity over cutoff, for healthy donor and pancreatic cancer sera, respectively;.

^†The score is calculated as (Freq_pancreaticx³√Intensity_pancreatic) − (Freq_healthyx³√Intensity_healthy) as described in ref. 20.