Fig. 3.

The optimized Cα model of the entire TRiC complex with its 16 subunits in the spatial arrangement determined by our cryo-EM structure. (A) End-on and side views of the TRiC complex. Same color scheme as in Fig. 1. (B) Cartoon diagram illustrating the arrangement of the 16 subunits in the two rings. We denote the TRiC subunits only by their CCT number. (C) Summary of near neighbors TRiC subunits identified by chemical cross-linking. Neighboring subunit pairs consistent with the indicated models are marked with a “+,” and those inconsistent with the indicated models are marked with a “−.”