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Crystallographic backbone renderings of (A) the GroEL homotetradecamer in (i) apo (41) and (ii) nucleotide/cochaperonin (GroES)-bound (42) states, and (B) HIV-1 gp120 in the CD4/17b bound state (29). In each panel of A, one protomer is rendered depicting the equatorial (blue), intermediate (white), and apical (red) domains. In B, inner domain is blue, outer is red, and the components of the bridging sheet, β2/3 and β20/21, are white and yellow, respectively.
