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. Author manuscript; available in PMC: 2010 Mar 19.
Published in final edited form as: Genet Epidemiol. 2008 Sep;32(6):505–512. doi: 10.1002/gepi.20323

TABLE IV.

Number of transmitted (T) or non-transmitted (NT) minor alleles to 298 CL/P cases (all populations combined)a from TAT and estimated odds ratios, plus parent-of-origin likelihood ratio test results about inequality of maternal vs. paternal transmission

Paternal
 Maternal
TAT
 TAT
 PO-LRTb
No. SNP name T NT P-value ORc T NT P-value ORc ORd P-value
1 rs7771980 9 8 0.808 1.13 16 18 0.732 0.89 0.79 0.692
2 rs2677104 25 30 0.500 0.83 22 24 0.768 0.92 1.10 0.811
3 rs2819855 36 34 0.811 1.06 37 25 0.128 1.48 1.40 0.342
4 rs2819854 35 36 0.906 0.97 37 29 0.325 1.28 1.32 0.417
5 rs910586 15 13 0.705 1.15 20 5 0.003 4.00 3.59 0.036
6 rs2819853 14 12 0.695 1.17 18 5 0.007 3.60 3.19 0.063
7 rs765724 15 13 0.705 1.15 20 6 0.006 3.33 2.97 0.065
8 rs1343799 14 12 0.695 1.17 18 5 0.007 3.60 3.19 0.063
9 rs2819861 13 12 0.841 1.08 19 5 0.004 3.80 3.73 0.036
10 rs2790103 16 11 0.336 1.45 20 5 0.003 4.00 2.86 0.092
11 rs2790093 15 12 0.564 1.25 18 5 0.007 3.60 2.99 0.079
12 rs2790098 15 12 0.564 1.25 19 6 0.009 3.17 2.60 0.110
13 rs4714854 15 12 0.564 1.25 19 6 0.009 3.17 2.60 0.110
14 rs9472494 15 14 0.853 1.07 22 7 0.005 3.14 2.99 0.051
15 rs2396442 17 14 0.590 1.21 24 8 0.005 3.00 2.51 0.086
16 rs1934328 41 17 0.002 2.41 35 33 0.808 1.06 0.44 0.029
17 rs7773875 33 21 0.102 1.57 32 32 1.000 1.00 0.65 0.245
18 rs7771889 36 18 0.014 2.00 40 31 0.285 1.29 0.64 0.238
19 rs10485422 15 13 0.705 1.15 17 6 0.022 2.83 2.42 0.135
20 rs6904353 13 14 0.847 0.93 18 11 0.194 1.64 1.78 0.294
21 rs13207392 16 15 0.857 1.07 19 7 0.019 2.71 2.50 0.102
22 rs7748231 13 13 1.000 1.00 18 11 0.194 1.64 1.64 0.373
23 rs10948237 13 14 0.847 0.93 18 11 0.194 1.64 1.78 0.294
24 rs1928533 12 13 0.841 0.92 15 13 0.705 1.15 1.27 0.671

Shading in the table indicates inferred LD blocks.

T, transmitted; NT, not transmitted; OR, odds ratio; CL/P, cleft lip with or without cleft palate; TAT, transmission asymmetry test; LD, linkage disequilibrium; SNP, single nucleotide polymorphism.

a

TAT analysis was used on trios with matings between two heterozygous parents deleted.

b

Parent-of-origin likelihood ratio test (PO-LRT) includes separate terms for imprinting.

c

OR(transmission): odds ratio of transmission of the minor allele.

d

OR: odds ratio for imprinting effect (i.e. differential transmission from mothers and from fathers).