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Hippocampal CB1 receptor immunoreactivity in representative interneurons sampled from the border of the stratum pyramidale (sp, top panels) and the dentate gyrus granule cell layer (gl, bottom panels) at several time points following pilocarpine-induced SE. Although decreased CB1 receptor immunostaining occurred throughout the hippocampus, interneuron immunoreactivity in many interneurons was preserved at 4 days (4d), 1 week (1w), and 2 weeks (2w) after SE. Scale bar = 50 μm.
