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. Author manuscript; available in PMC: 2010 Sep 1.
Published in final edited form as: Cancer Res. 2009 Aug 18;69(17):6823–6830. doi: 10.1158/0008-5472.CAN-09-1684

Figure 3. Stat3 ablation leads to decreased VEGF production and angiogenesis.

Figure 3

Decreased VEGF protein levels in Stat3flx/flx/NIC tumors by immunoblotting (A) and ELISA (B) assays (average VEGF quantity ±s.e.m.). (C) Immunohistochemical staining using a CD31 antibody (left panel) and quantification of the average number (±s.e.m.) of CD31 positive pixels (right panel). Scale bar: 100 μm. (p values were calculated using a two-tailed student’s t-test; *p=0.017).

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