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Frequency of different subsets of BCG-specific CD4+ T cells, based on expression of CD45RA, CCR7 and CD27 among IFN-γ+ and IL-2+ (A), and IFN-γ+IL-2+ (B), expressing CD4+ T cells. (C) Frequency of these cells among cytokine-negative, i.e., mostly mycobacteria-non-specific, CD4+ T cells. The horizontal line represents the median and the whiskers the interquartile range. *, p<0.05; ns, p≥0.05.
