Table 4. Cytotoxic activity, determined as CD107a mobilization of T lymphocytes cell lines against autologous CSCs.
T cells | CD4/CD8 | Target cells | |||||
---|---|---|---|---|---|---|---|
Ly alone | 070104 CSCs | +W6/32 | +L243 | 0627 CSCs HLA mismatched | QKT3 | ||
2 | 5/95* | 1† | 20 | 9 | 17 | 7 | 56 |
3 | 96/4 | 1 | 2 | 1 | 1 | 1 | 8 |
10 | 20/76 | 2 | 13 | ND | ND | 1 | 24 |
NOTE: OKT3 stimulation of T cells was used as positive control of CD107a mobilization. Data are expressed as % of positive and represent averages of duplicates with an SD of ≤10.
Abbreviation: ND, not determined.
Results represent the percentage of CD4- and CD8-positive T cells.
Results represent the percentage of CD107a-positive T cells.