Fig. 3.

Direct contrast of original music vs. altered music in healthy newborns (n = 18, random effects group analysis; P < 0.05 at the voxel level, uncorrected) overlaid on a T2-weighted image from a single newborn (note that the spatial resolution of the functional group data is lower compared with the anatomical image). Regions more active for original music are shown in orange/yellow, and regions more active for altered music are shown in blue. Two axial slices show a stronger activation of the left inferior frontal gyrus in response to altered music. The slices also show a stronger activation of (posterior) auditory cortex in response to original music. The two coronal slices show activation of the left amygdala-hippocampal complex (and of the ventral striatum) for altered music and activation of the right amygdala-hippocampal complex for original music. The two sagittal slices show the larger right superior temporal activation for original music.