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In vitro susceptibility of sodC mutant S. typhimurium to extracellular superoxide and NO. Wild-type or sodC mutant (MF1005) bacteria in PBS with 250 μM hypoxanthine were treated with 0.1 unit/ml xanthine oxidase (XO), 1 mM SPER/NO (NO), or the combination of xanthine oxidase and SPER/NO (XONO) as described in Materials and Methods.
