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. 2009 May;11(5):1139–1148. doi: 10.1089/ars.2009.2440

FIG. 6.

FIG. 6.

Purification of honokiol from Magnolia. Protection of magnolol with dimethoxypropane to make the magnolol-acetonide enables honokiol to be purified via chromatography. Without the protection, both magnolol and honokiol, which are structural isomers of each other, have the same polarity and cannot be separated. The protected magnolol can be deprotected by using acid.