TABLE 1.
Baseline characteristics, lipids, and noncholesterol sterols
| Simvastatin 80 mg | Ezetimibe/Simvastatin 10/80 mg | P | |
|---|---|---|---|
| Subjects (n) | 289 | 302 | |
| Age (years) | 45.5 ± 9.6 | 46.4 ± 8.9 | 0.271 |
| Male gender (n) | 145 (50.2%) | 161 (53.3%) | 0.583 |
| BMI (kg/m2) | 26.9 ± 4.3 | 27.5 ± 4.7 | 0.108 |
| Total cholesterol (mmol/l) | 10.33 ± 1.86 | 10.35 ± 1.83 | 0.923 |
| LDL-C (mmol/l) | 8.22 ± 1.80 | 8.25 ± 1.75 | 0.805 |
| HDL-cholesterol (mmol/l) | 1.19 ± 0.30 | 1.21 ± 0.29 | 0.494 |
| Triglycerides (mmol/l) | 1.82 [ 0.54 - 6.75] | 1.77 [0.49 – 8.08] | 0.380 |
| Campesterol (mg/dl) | 0.76 ± 0.38 | 0.82 ± 0.46 | 0.118 |
| Sitosterol (mg/dl) | 0.54 ± 0.26 | 0.56 ± 0.27 | 0.376 |
| Lathosterol (mg/dl) | 0.53 ± 0.20 | 0.52 ± 0.21 | 0.392 |
| Campesterol/TC ratio (μg/mg) | 1.90 ± 0.88 | 2.02 ± 1.01 | 0.125 |
| Sitosterol/TC (μg/mg) | 1.36 ± 0.59 | 1.40 ± 0.59 | 0.431 |
| Lathosterol/TC ratio (μg/mg) | 1.35 ± 0.48 | 1.30 ± 0.50 | 0.228 |
Data are presented as means ± SD, median [range], or number (%). Analyses were performed with independent Student's t-test. For gender, Chi2 test was used. As triglyceride data were skewed, data were log-transformed prior to testing; however, untransformed medians and range are presented.