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. 2010 Apr;51(4):755–762. doi: 10.1194/jlr.M001487

TABLE 3.

Associations between baseline noncholesterol sterols and change in noncholesterol sterols

Change in Noncholesterol Sterols Simvastatin 80 mg (N = 289)
Ezetimibe/Simvastatin 10/80 mg (N = 302)
β P β P
Δ Lathosterol/TC, μg/mga
Lathosterol/TC, μg/mg −0.752 <0.001 −0.623 <0.001
Campesterol/TC, μg/mg −0.043 0.316 −0.049 0.313
Sitosterol/TC, μg/mg −0.051 0.247 −0.048 0.336
Δ Lathosterol, mg/dlb
Lathosterol, mg/dl −0.853 <0.001 −0.832 <0.001
Campesterol, mg/dl −0.035 0.310 −0.027 0.435
Sitosterol, mg/dl −0.025 0.470 −0.025 0.475
Δ Campesterol/TC, μg/mgc
Campesterol/TC, μg/mg −0.210 0.001 −0.898 <0.001
Sitosterol/TC, μg/mg −0.189 0.003 −0.695 <0.001
Lathosterol/TC, μg/mg −0.122 0.050 −0.043 0.175
Δ Campesterol, mg/dld
Campesterol, mg/dl −0.676 <0.001 −0.973 <0.001
Sitosterol, mg/dl −0.567 <0.001 −0.821 <0.001
Lathosterol, mg/dl −0.116 0.015 −0.005 0.754
Δ Sitosterol/TC, μg/mge
Sitosterol/TC, μg/mg −0.164 0.009 −0.719 <0.001
Campesterol/TC, μg/mg −0.117 0.057 −0.632 <0.001
Lathosterol/TC, μg/mg −0.122 0.053 −0.052 0.286
Δ Sitosterol, mg/dl f
Sitosterol, mg/dl −0.589 <0.001 −0.940 <0.001
Campesterol, mg/dl −0.543 <0.001 −0.829 <0.001
Lathosterol, mg/dl −0.118 0.025 −0.013 0.570

Data were analyzed by multiple regression. β represents the standardized β coefficient.

a

Corrected for baseline lathosterol/TC and BMI.

b

Corrected for baseline lathosterol and BMI.

c

Corrected for baseline campesterol/TC, lathosterol/TC, and BMI.

d

Corrected for baseline campesterol, lathosterol, and BMI.

e

Corrected for baseline sitosterol/TC, lathosterol/TC, and BMI.

f

Corrected for baseline sitosterol, lathosterol, and BMI.