TABLE 3.
Change in Noncholesterol Sterols | Simvastatin 80 mg (N = 289) |
Ezetimibe/Simvastatin 10/80 mg (N = 302) |
||
---|---|---|---|---|
β | P | β | P | |
Δ Lathosterol/TC, μg/mga | ||||
Lathosterol/TC, μg/mg | −0.752 | <0.001 | −0.623 | <0.001 |
Campesterol/TC, μg/mg | −0.043 | 0.316 | −0.049 | 0.313 |
Sitosterol/TC, μg/mg | −0.051 | 0.247 | −0.048 | 0.336 |
Δ Lathosterol, mg/dlb | ||||
Lathosterol, mg/dl | −0.853 | <0.001 | −0.832 | <0.001 |
Campesterol, mg/dl | −0.035 | 0.310 | −0.027 | 0.435 |
Sitosterol, mg/dl | −0.025 | 0.470 | −0.025 | 0.475 |
Δ Campesterol/TC, μg/mgc | ||||
Campesterol/TC, μg/mg | −0.210 | 0.001 | −0.898 | <0.001 |
Sitosterol/TC, μg/mg | −0.189 | 0.003 | −0.695 | <0.001 |
Lathosterol/TC, μg/mg | −0.122 | 0.050 | −0.043 | 0.175 |
Δ Campesterol, mg/dld | ||||
Campesterol, mg/dl | −0.676 | <0.001 | −0.973 | <0.001 |
Sitosterol, mg/dl | −0.567 | <0.001 | −0.821 | <0.001 |
Lathosterol, mg/dl | −0.116 | 0.015 | −0.005 | 0.754 |
Δ Sitosterol/TC, μg/mge | ||||
Sitosterol/TC, μg/mg | −0.164 | 0.009 | −0.719 | <0.001 |
Campesterol/TC, μg/mg | −0.117 | 0.057 | −0.632 | <0.001 |
Lathosterol/TC, μg/mg | −0.122 | 0.053 | −0.052 | 0.286 |
Δ Sitosterol, mg/dl f | ||||
Sitosterol, mg/dl | −0.589 | <0.001 | −0.940 | <0.001 |
Campesterol, mg/dl | −0.543 | <0.001 | −0.829 | <0.001 |
Lathosterol, mg/dl | −0.118 | 0.025 | −0.013 | 0.570 |
Data were analyzed by multiple regression. β represents the standardized β coefficient.
Corrected for baseline lathosterol/TC and BMI.
Corrected for baseline lathosterol and BMI.
Corrected for baseline campesterol/TC, lathosterol/TC, and BMI.
Corrected for baseline campesterol, lathosterol, and BMI.
Corrected for baseline sitosterol/TC, lathosterol/TC, and BMI.
Corrected for baseline sitosterol, lathosterol, and BMI.